Preheat your oven to 400°F (200°C).
Begin by cleaning the clams. Scrub them under cold running water to remove any dirt or sand.
In a large skillet or pan with a lid, pour the white wine, and add the minced garlic. Place the cleaned clams in the skillet.
Cover the skillet with a lid and cook the clams over medium-high heat for 5-7 minutes or until they open. Shake the pan occasionally to help distribute the heat evenly. Discard any clams that do not open after this time.
Once the clams have opened, remove them from the skillet and set them aside to cool slightly. Be sure to reserve the cooking liquid.
Gently detach the clam meat from one half of the shell, leaving it on the half-shell. Discard the other half of the shell.
Place the clam shells on a baking sheet or ovenproof dish.
In a bowl, combine the breadcrumbs (e.g., 1/4 cup or adjust to your liking), chopped parsley, grated Parmesan cheese, melted butter, and a pinch of salt and black pepper. You can add a dash of crushed red pepper flakes if you like heat.
Spoon the breadcrumb mixture onto each clam in its shell. I suggest about ½ to 1 teaspoon or so on each (depending on the size of the clams) – you don’t want to overpower the clam with the topping – you can also opt to sprinkle the topping on each clam.
Drizzle a little of the reserved cooking liquid from the skillet over each clam to moisten them.
Bake the clams in the oven for 10-12 minutes or until the tops are golden brown and crispy.
Remove the baked clams from the oven, garnish with lemon wedges (and additional parsley if desired), and serve hot with hot sauce and lemon wedges.